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NDC80 Antibody

CAT: 0223-61-289Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-289Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
NCBI Gene ID
10403
Swiss Prot
O14777
Accession Number
O14777
Host
Rabbit
Reactivity
Human
Immunogen
This NDC80 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 508-539 amino acids from human NDC80.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
NDC80
NCBI Official Name
Kinetochore protein NDC80 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Chen Y., et al.Mol. Cell. Biol. 17:6049-6056 (1997) .
Background Reference 02
Chen Y., et al.J. Biol. Chem. 272:24081-24087 (1997) .
Background Reference 03
Zheng L., et al.Mol. Cell. Biol. 19:5417-5428 (1999) .
Background Reference 04
Zheng L., et al.Mol. Cell. Biol. 20:3529-3537 (2000) .
Other Product Names
Kinetochore protein NDC80 homolog, Highly expressed in cancer protein, Kinetochore protein Hec1, HsHec1, Kinetochore-associated protein 2, Retinoblastoma-associated protein HEC, NDC80, HEC, HEC1, KNTC2
Tested Applications
WB
Physical Properties
Liquid

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