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GC Antibody

CAT: 0223-61-272Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-272Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
NCBI Gene ID
2638
Swiss Prot
P02774
Accession Number
P02774
Host
Rabbit
Reactivity
Human
Immunogen
This GC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 442-473 amino acids from human GC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
GC
NCBI Official Name
Vitamin D-binding protein
NCBI Organism
Homo sapiens
Background Reference 01
Cooke N.E., et al.J. Clin. Invest. 76:2420-2424 (1985) .
Background Reference 02
Yang F., et al.Proc. Natl. Acad. Sci. U.S.A. 82:7994-7998 (1985) .
Background Reference 03
Braun A., et al.Biochim. Biophys. Acta 1216:385-394 (1993) .
Background Reference 04
Witke W.F., et al.Genomics 16:751-754 (1993) .
Other Product Names
Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, GC
Tested Applications
WB
Protein ID
139641
Physical Properties
Liquid

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