HEXIM2 Antibody

CAT: 0223-61-257Size: 200 µLDry Ice: NoHazardous: No
CAT#:0223-61-257Size:200 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
NCBI Gene ID
124790
Swiss Prot
Q96MH2
Accession Number
Q96MH2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This HEXIM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 235-269 amino acids from of human HEXIM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:8000
Symbol
HEXIM2
NCBI Official Name
Protein HEXIM2
NCBI Organism
Homo sapiens
Background Reference 01
Petroziello J., et al.Oncogene 23:7734-7745 (2004) .
Background Reference 02
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Background Reference 03
Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Background Reference 04
Byers S.A., et al.J. Biol. Chem. 280:16360-16367 (2005) .
Other Product Names
Protein HEXIM2, Hexamethylene bis-acetamide-inducible protein 2, HEXIM2
Tested Applications
WB
Protein ID
74732374
Physical Properties
Liquid