MTUS1 Antibody

• Background:

  Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.

• NCBI Gene ID:

  57509

• Swiss Prot:

  Q9ULD2

• Accession Number:

  Q9ULD2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MTUS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-226 amino acids from human MTUS1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  141 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  MTUS1

• NCBI Official Name:

  Microtubule-associated tumor suppressor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kinjo T., et al.J. Hum. Genet. 45:12-17 (2000) .

• Background Reference 02:

  Seibold S., et al.FASEB J. 17:1180-1182 (2003) .

• Background Reference 03:

  Nouet S., et al.J. Biol. Chem. 279:28989-28997 (2004) .

• Background Reference 04:

  Ota T., et al.Nat. Genet. 36:40-45 (2004) .

• Other Product Names:

  Microtubule-associated tumor suppressor 1, AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Mitochondrial tumor suppressor 1, MTUS1, ATBP, ATIP, GK1, KIAA1288, MTSG1

• Tested Applications:

  WB

• Protein ID:

  158706128

• Physical Properties:

  Liquid