LLGL2 Antibody

• Background :

  The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

• NCBI Gene ID :

  3993

• Swiss Prot :

  Q6P1M3

• Accession Number :

  Q6P1M3

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This LLGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human LLGL2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  113 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:2000

• Symbol :

  LLGL2

• NCBI Official Name :

  Lethal (2) giant larvae protein homolog 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Yasumi, M., et al., J. Biol. Chem. 280 (8) :6761-6765 (2005) . Katoh, M., et al., Int. J. Oncol. 24 (3) :737-742 (2004) .

• Other Product Names :

  Lethal (2) giant larvae protein homolog 2, HGL, LLGL2

• Tested Applications :

  WB

• Protein ID :

  93204600

• Physical Properties :

  Liquid