LLGL2 Antibody

• Background:

  The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

• NCBI Gene ID:

  3993

• Swiss Prot:

  Q6P1M3

• Accession Number:

  Q6P1M3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This LLGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 940-973 amino acids from the C-terminal region of human LLGL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  113 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  LLGL2

• NCBI Official Name:

  Lethal (2) giant larvae protein homolog 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yasumi, M., et al., J. Biol. Chem. 280 (8) :6761-6765 (2005) . Katoh, M., et al., Int. J. Oncol. 24 (3) :737-742 (2004) .

• Other Product Names:

  Lethal (2) giant larvae protein homolog 2, HGL, LLGL2

• Tested Applications:

  WB

• Protein ID:

  93204600

• Physical Properties:

  Liquid