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NAA10 Antibody

CAT: 0223-61-219Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-219Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development.
NCBI Gene ID
8260
Swiss Prot
P41227
Accession Number
P41227
Host
Rabbit
Reactivity
Human
Immunogen
This NAA10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 135-167 amino acids from the Central region of human NAA10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
NAA10
NCBI Official Name
N-alpha-acetyltransferase 10
NCBI Organism
Homo sapiens
Background Reference 01
Tribioli C., et al.Hum. Mol. Genet. 3:1061-1068 (1994) .
Background Reference 02
Arnesen T., et al.Biochem. J. 386:433-443 (2005) .
Background Reference 03
Ross M.T., et al.Nature 434:325-337 (2005) .
Background Reference 04
Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Other Product Names
N-alpha-acetyltransferase 10, 2.3.1.-, 2.3.1.88, N-terminal acetyltransferase complex ARD1 subunit homolog A, NatA catalytic subunit Naa10, NAA10, ARD1, ARD1A, TE2
Tested Applications
WB
Protein ID
728880
Physical Properties
Liquid

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