CERS4 Antibody

• Background:

  May be either a bona fide (dihydro) ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity) .

• NCBI Gene ID:

  79603

• Swiss Prot:

  Q9HA82

• Accession Number:

  Q9HA82

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CERS4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from human CERS4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  46 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CERS4

• NCBI Official Name:

  Ceramide synthase 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ota T., et al.Nat. Genet. 36:40-45 (2004) .

• Background Reference 02:

  Grimwood J., et al.Nature 428:529-535 (2004) .

• Background Reference 03:

  Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

• Other Product Names:

  Ceramide synthase 4, CerS4, LAG1 longevity assurance homolog 4, CERS4, LASS4

• Tested Applications:

  WB, Flow

• Protein ID:

  296434561

• Physical Properties:

  Liquid