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PDS5B Antibody

CAT: 0223-61-175Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-175Size:200 µL
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Background
Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.
NCBI Gene ID
23047
Swiss Prot
Q9NTI5
Accession Number
Q9NTI5
Host
Rabbit
Reactivity
Human
Immunogen
This PDS5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1197-1228 amino acids from human PDS5B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
165 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
PDS5B
NCBI Official Name
Sister chromatid cohesion protein PDS5 homolog B
NCBI Organism
Homo sapiens
Background Reference 01
Geck P., et al.J. Steroid Biochem. Mol. Biol. 63:211-218 (1997) .
Background Reference 02
Geck P., et al.J. Steroid Biochem. Mol. Biol. 68:41-50 (1999) .
Background Reference 03
Nagase T., et al.DNA Res. 6:63-70 (1999) .
Background Reference 04
Nakajima D., et al.DNA Res. 9:99-106 (2002) .
Other Product Names
Sister chromatid cohesion protein PDS5 homolog B, Androgen-induced proliferation inhibitor, Androgen-induced prostate proliferative shutoff-associated protein AS3, PDS5B
Tested Applications
WB
Protein ID
74725312
Physical Properties
Liquid

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