DNASE1L2 Antibody

• Background:

  Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells.

• NCBI Gene ID:

  1775

• Swiss Prot:

  Q92874

• Accession Number:

  Q92874

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DNASE1L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 199-229 amino acids from human DNASE1L2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  33 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  DNASE1L2

• NCBI Official Name:

  Deoxyribonuclease-1-like 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rodriguez A.M., et al.Genomics 42:507-513 (1997) .

• Background Reference 02:

  Shiokawa D., et al.Genomics 84:95-105 (2004) .

• Background Reference 03:

  Ota T., et al.Nat. Genet. 36:40-45 (2004) .

• Background Reference 04:

  Martin J., et al.Nature 432:988-994 (2004) .

• Other Product Names:

  Deoxyribonuclease-1-like 2, 3.1.21.-, DNase I homolog protein DHP1, Deoxyribonuclease I-like 2, DNase I-like 2, DNASE1L2, DHP1, DNAS1L2

• Tested Applications:

  WB

• Protein ID:

  2494172

• Physical Properties:

  Liquid