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Dsk2 Antibody

CAT: 0223-61-128Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-128Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome; it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.
NCBI Gene ID
29978
Swiss Prot
Q9UHD9
Accession Number
Q9UHD9
Host
Rabbit
Reactivity
Human
Immunogen
This Dsk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human Dsk2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
66 kDa
Fragment
Rabbit Ig
Symbol
UBQLN2
NCBI Official Name
Ubiquilin-2
NCBI Organism
Homo sapiens
Background Reference 01
Walters, K.J., et al., Biochemistry 41 (6) :1767-1777 (2002) .
Background Reference 02
Kleijnen, M.F., et al., Mol. Cell 6 (2) :409-419 (2000) .
Background Reference 03
Ueki, N., et al., Nat. Biotechnol. 16 (13) :1338-1342 (1998) .
Other Product Names
Ubiquilin-2, Chap1, DSK2 homolog, Protein linking IAP with cytoskeleton 2, PLIC-2, hPLIC-2, Ubiquitin-like product Chap1/Dsk2, UBQLN2, N4BP4, PLIC2
Tested Applications
WB, IHC-P
Protein ID
124056593
Physical Properties
Liquid

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