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CRX Antibody

CAT: 0223-61-066Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-066Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
NCBI Gene ID
1406
Swiss Prot
O43186
Accession Number
O43186
Host
Rabbit
Reactivity
Human
Immunogen
This CRX antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 294-297 amino acids from the C-terminal region of human CRX.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CRX
NCBI Official Name
Cone-rod homeobox protein
NCBI Organism
Homo sapiens
Background Reference 01
Freund C.L., et al.Cell 91:543-553 (1997) .
Background Reference 02
Kalnine N., et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Background Reference 03
Grimwood J., et al.Nature 428:529-535 (2004) .
Background Reference 04
Roni V., et al.BMC Genomics 8:42-42 (2007) .
Other Product Names
Cone-rod homeobox protein, CRX, CORD2
Tested Applications
WB
Physical Properties
Liquid

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