REG3A Antibody

• Background:

  Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.

• NCBI Gene ID:

  5068

• Swiss Prot:

  Q06141

• Accession Number:

  Q06141

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This REG3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 129-163 amino acids from the C-terminal region of human REG3A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  19 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  REG3A

• NCBI Official Name:

  Regenerating islet-derived protein 3-alpha

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Itoh T., et al.Biochim. Biophys. Acta 1172:184-186 (1993) .

• Background Reference 02:

  Orelle B., et al.J. Clin. Invest. 90:2284-2291 (1992) .

• Background Reference 03:

  Lasserre C., et al.Cancer Res. 52:5089-5095 (1992) .

• Background Reference 04:

  Dusetti N.J., et al.Genomics 19:108-114 (1994) .

• Other Product Names:

  Regenerating islet-derived protein 3-alpha, REG-3-alpha, Hepatointestinal pancreatic protein, HIP/PAP, Human proislet peptide, Pancreatitis-associated protein 1, Regenerating islet-derived protein III-alpha, Reg III-alpha, Regenerating islet-derived protein 3-alpha 165 kDa form, Regenerating islet-derived protein 3-alpha 15 kDa form, REG3A, HIP, PAP, PAP1

• Tested Applications:

  WB, Flow

• Protein ID:

  464341

• Physical Properties:

  Liquid