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Mouse Tfap2a Antibody

CAT: 0223-61-019Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-019Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
NCBI Gene ID
21418
Swiss Prot
P34056
Accession Number
P34056
Host
Rabbit
Reactivity
Mouse
Immunogen
This mouse Tfap2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the Central region of mouse Tfap2a.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Tfap2a
NCBI Official Name
Transcription factor AP-2-alpha
NCBI Organism
Mus musculus
Background Reference 01
Moser M., et al.Nucleic Acids Res. 21:4844-4844 (1993) .
Background Reference 02
Meier P., et al.Dev. Biol. 169:1-14 (1995) .
Background Reference 03
Carninci P., et al.Science 309:1559-1563 (2005) .
Background Reference 04
Mitchell P.J., et al.Genes Dev. 5:105-119 (1991) .
Other Product Names
Transcription factor AP-2-alpha, AP2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2, Tfap2a, Ap2tf, Tcfap2a
Tested Applications
WB
Physical Properties
Liquid

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