TFAP2B Antibody

CAT: 0223-56-956Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-956Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq].
NCBI Gene ID
7021
Swiss Prot
Q92481
Accession Number
Q92481
Host
Rabbit
Reactivity
Human
Immunogen
This TFAP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-462 amino acids from the C-terminal region of human TFAP2B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TFAP2B
NCBI Official Name
Transcription factor AP-2-beta
NCBI Organism
Homo sapiens
Background Reference 01
Li, X., et al. Genes Chromosomes Cancer 49 (9) :819-830 (2010)
Background Reference 02
Hotta, K., et al. J. Hum. Genet. (2010) In press :
Background Reference 03
Ugi, S., et al. Obesity (Silver Spring) 18 (7) :1277-1282 (2010)
Background Reference 04
Nordquist, N., et al. Brain Res. 1305 SUPPL, S20-S26 (2009) :
Other Product Names
Transcription factor AP-2-beta, AP2-beta, Activating enhancer-binding protein 2-beta, TFAP2B
Tested Applications
WB
Protein ID
152031557
Physical Properties
Liquid

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