JAM3 Antibody

• Background:

  Participates in cell-cell adhesion. It is a counter- receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN) . The soluble form is a mediator of angiogenesis.

• NCBI Gene ID:

  83700

• Swiss Prot:

  Q9BX67

• Accession Number:

  Q9BX67

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  This JAM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 261-295 amino acids from the C-terminal region of human JAM3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  JAM3

• NCBI Official Name:

  Junctional adhesion molecule C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Arrate M.P., et al.J. Biol. Chem. 276:45826-45832 (2001) .

• Background Reference 02:

  Aurrand-Lions M.A., et al.Blood 98:3699-3707 (2001) .

• Background Reference 03:

  Santoso S., et al.J. Exp. Med. 196:679-691 (2002) .

• Background Reference 04:

  Phillips H.M., et al.Genomics 79:475-478 (2002) .

• Other Product Names:

  Junctional adhesion molecule C, JAM-C, JAM-2, Junctional adhesion molecule 3, JAM-3, JAM3

• Tested Applications:

  WB

• Protein ID:

  51701611

• Physical Properties:

  Liquid