ECE2 Antibody

CAT: 0223-60-991Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-991Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
NCBI Gene ID
9718
Swiss Prot
O60344
Accession Number
O60344
Host
Rabbit
Reactivity
Human
Immunogen
This ECE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the Central region of human ECE2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
100 kDa
Fragment
Rabbit Ig
Symbol
ECE2
NCBI Official Name
Endothelin-converting enzyme 2
NCBI Organism
Homo sapiens
Background Reference 01
Lorenzo M.-N., et al. Biochim. Biophys. Acta 1522:46-52 (2001) .
Background Reference 02
Funke-Kaiser H., et al. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Background Reference 03
Nagase T., et al. DNA Res. 5:31-39 (1998) .
Background Reference 04
Clark H.F., et al. Genome Res. 13:2265-2270 (2003) .
Other Product Names
Endothelin-converting enzyme 2, ECE-2, Methyltransferase-like region, 211-, Endothelin-converting enzyme 2 region, ECE2, KIAA0604
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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