VEGFC Antibody

• Background:

  VEGF3 is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

• NCBI Gene ID:

  7424

• Swiss Prot:

  P49767

• Accession Number:

  P49767

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This VEGFC (VEGF3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 amino acids from the Central region of human VEGFC (VEGF3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  47 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  VEGFC

• NCBI Official Name:

  Vascular endothelial growth factor C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Byeon, J.S., et al., J. Gastroenterol. Hepatol. 19 (6) :648-654 (2004) .

• Background Reference 02:

  Su, J.L., et al., Cancer Res. 64 (2) :554-564 (2004) .

• Background Reference 03:

  Yan, C., et al., World J. Gastroenterol. 10 (6) :783-790 (2004) .

• Background Reference 04:

  Hsieh, C.Y., et al., J. Biomed. Sci. 11 (2) :249-259 (2004) .

• Other Product Names:

  Vascular endothelial growth factor C, VEGF-C, Flt4 ligand, Flt4-L, Vascular endothelial growth factor-related protein, VRP, VEGFC

• Tested Applications:

  WB, IHC-P

• Protein ID:

  1718154

• Physical Properties:

  Liquid