EDC3 Antibody

• Background:

  EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]) .

• NCBI Gene ID:

  80153

• Swiss Prot:

  Q96F86

• Accession Number:

  Q96F86

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This EDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human EDC3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  56 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  EDC3

• NCBI Official Name:

  Enhancer of mRNA-decapping protein 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tritschler, F., et al. Mol. Cell 33 (5) :661-668 (2009)

• Background Reference 02:

  Ling, S.H., et al. Mol. Cell. Biol. 28 (19) :5965-5976 (2008)

• Background Reference 03:

  Tritschler, F., et al. Mol. Cell. Biol. 27 (24) :8600-8611 (2007)

• Background Reference 04:

  Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

• Other Product Names:

  Enhancer of mRNA-decapping protein 3, LSM16 homolog, YjeF N-terminal domain-containing protein 2, YjeF_N2, hYjeF_N2, YjeF domain-containing protein 1, EDC3, LSM16, YJDC, YJEFN2

• Tested Applications:

  WB

• Protein ID:

  74731669

• Physical Properties:

  Liquid