CCT7 Antibody

• Background:

  This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.

• NCBI Gene ID:

  10574

• Swiss Prot:

  Q99832

• Accession Number:

  Q99832

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CCT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the N-terminal region of human CCT7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  59 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CCT7

• NCBI Official Name:

  T-complex protein 1 subunit eta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mukherjee, K., et al. BMC Evol. Biol. 10, 64 (2010) :

• Background Reference 02:

  Zebol, J.R., et al. Int. J. Biochem. Cell Biol. 41 (4) :822-827 (2009)

• Background Reference 03:

  Guo, D., et al. Biochem. Biophys. Res. Commun. 337 (4) :1308-1318 (2005)

• Background Reference 04:

  Hanafy, K.A., et al. J. Biol. Chem. 279 (45) :46946-46953 (2004)

• Other Product Names:

  T-complex protein 1 subunit eta, TCP-1-eta, CCT-eta, HIV-1 Nef-interacting protein, CCT7, CCTH, NIP7-1

• Tested Applications:

  WB

• Protein ID:

  3041738

• Physical Properties:

  Liquid