CCT5 Antibody

• Background:

  The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP) . Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.

• NCBI Gene ID:

  22948

• Swiss Prot:

  P48643

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCT5 (NP_036205.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 60kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  CCT5

• Positive Control 2:

  BT-474

• Positive Control 3:

  MCF7

• Positive Control 4:

  U-937

• Positive Control 5:

  Mouse spleen

• Positive Control 6:

  Mouse thymus

• NCBI Official Name:

  Chaperonin containing TCP1, subunit 5 (epsilon)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CCT5, CCT-epsilon, CCTE, KIAA0098, TCP-1-epsilon, HEL-S-69

• Tested Applications:

  WB

• Physical Properties:

  Liquid