CCT8 Antibody

• Background:

  Molecular chaperone; CCT8 assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

• NCBI Gene ID:

  10694

• Swiss Prot:

  P50990

• Accession Number:

  P50990

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CCT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human CCT8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  60 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CCT8

• NCBI Official Name:

  T-complex protein 1 subunit theta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mukherjee, K., et al. BMC Evol. Biol. 10, 64 (2010) :

• Background Reference 02:

  Zebol, J.R., et al. Int. J. Biochem. Cell Biol. 41 (4) :822-827 (2009)

• Background Reference 03:

  Kim, S.C., et al. Mol. Cell 23 (4) :607-618 (2006)

• Background Reference 04:

  Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :

• Other Product Names:

  T-complex protein 1 subunit theta, TCP-1-theta, CCT-theta, Renal carcinoma antigen NY-REN-15, CCT8, C21orf112, CCTQ, KIAA0002

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  9988062

• Physical Properties:

  Liquid