WBSCR22 Antibody

• Background:

  This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23.

• NCBI Gene ID:

  114049

• Swiss Prot:

  O43709

• Accession Number:

  O43709

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This WBSCR22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids from the C-terminal region of human WBSCR22.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  32 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  WBSCR22

• NCBI Official Name:

  Probable 18S rRNA (guanine-N (7) ) -methyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 02:

  Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)

• Background Reference 03:

  Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (44) :15724-15729 (2004)

• Background Reference 04:

  Merla, G., et al. Hum. Genet. 110 (5) :429-438 (2002)

• Other Product Names:

  Probable 18S rRNA (guanine-N (7) ) -methyltransferase, 211-, Bud site selection protein 23 homolog, Metastasis-related methyltransferase 1, Williams-Beuren syndrome chromosomal region 22 protein, WBSCR22, MERM1

• Tested Applications:

  WB

• Physical Properties:

  Liquid