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GEMIN4 Antibody

CAT: 0223-60-915Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-915Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems) . The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
NCBI Gene ID
50628
Swiss Prot
P57678
Accession Number
P57678
Host
Rabbit
Reactivity
Human
Immunogen
This GEMIN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the N-terminal region of human GEMIN4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
120 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GEMIN4
NCBI Official Name
Gem-associated protein 4
NCBI Organism
Homo sapiens
Background Reference 01
Kim, J.S., et al. Mol. Carcinog. 49 (10) :913-921 (2010)
Background Reference 02
Wilker, E.H., et al. Environ. Health Perspect. 118 (7) :943-948 (2010)
Background Reference 03
Boni, V., et al. Pharmacogenomics J. (2010) In press :
Background Reference 04
Clague, J., et al. Mol. Carcinog. 49 (2) :183-189 (2010)
Other Product Names
Gem-associated protein 4, Gemin-4, Component of gems 4, p97, GEMIN4
Tested Applications
WB
Protein ID
322510030
Physical Properties
Liquid

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