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VANGL2 Antibody

CAT: 0223-60-897Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-897Size:400 µL
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Background
Planar cell polarity (PCP) is the term given to global cell polarization, such as the alignment of mammalian body hair along the anterior-posterior axis or the orientation of steriocilia bundles in the inner ear. VANGL2 is a PCP protein that is involved in the transmission of directional cues to align either individual cells within an epithelial sheet or multicellular clusters, which polarize as a group (Devenport and Fuchs, 2008 [PubMed 18849982]) .
NCBI Gene ID
57216
Swiss Prot
Q9ULK5
Accession Number
Q9ULK5
Host
Rabbit
Reactivity
Mouse
Immunogen
This VANGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human VANGL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
VANGL2
NCBI Official Name
Vang-like protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Lei, Y.P., et al. N. Engl. J. Med. 362 (23) :2232-2235 (2010)
Background Reference 02
Yates, L.L., et al. Hum. Mol. Genet. 19 (11) :2251-2267 (2010)
Background Reference 03
Cantrell, V.A., et al. Cancer Lett. 287 (1) :54-61 (2010)
Background Reference 04
Need, A.C., et al. Hum. Mol. Genet. 18 (23) :4650-4661 (2009)
Other Product Names
Vang-like protein 2, Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2, VANGL2, KIAA1215, STB1
Tested Applications
WB
Protein ID
38258849
Physical Properties
Liquid

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