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MMEL1 Antibody

CAT: 0223-60-895Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-895Size:400 µL
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Background
The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.
NCBI Gene ID
79258
Swiss Prot
Q495T6
Accession Number
Q495T6
Host
Rabbit
Reactivity
Human
Immunogen
This MMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human MMEL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
89 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MMEL1
NCBI Official Name
Membrane metallo-endopeptidase-like 1
NCBI Organism
Homo sapiens
Background Reference 01
Van der Helm-van Mil, A.H., et al. Ann. Rheum. Dis. 69 (9) :1694-1696 (2010)
Background Reference 02
Hirschfield, G.M., et al. Nat. Genet. 42 (8) :655-657 (2010)
Background Reference 03
Stahl, E.A., et al. Nat. Genet. 42 (6) :508-514 (2010)
Background Reference 04
Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)
Other Product Names
Membrane metallo-endopeptidase-like 1, Membrane metallo-endopeptidase-like 2, NEP2 (m), Neprilysin II, NEPII, Neprilysin-2, NEP2, NL2, Membrane metallo-endopeptidase-like 1, soluble form, Neprilysin-2 secreted, NEP2 (s), MMEL1, MELL1, MMEL2, NEP2
Tested Applications
WB
Protein ID
114150028
Physical Properties
Liquid

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