MAK Antibody

• Background:

  The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.

• NCBI Gene ID:

  4117

• Swiss Prot:

  P20794

• Accession Number:

  P20794

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 595-623 amino acids from the C-terminal region of human MAK.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  71 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MAK

• NCBI Official Name:

  Serine/threonine-protein kinase MAK

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Fu, Z., et al. Mol. Cell. Biol. 26 (22) :8639-8654 (2006)

• Background Reference 02:

  Ma, A.H., et al. Cancer Res. 66 (17) :8439-8447 (2006)

• Background Reference 03:

  Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)

• Background Reference 04:

  Xia, L., et al. J. Biol. Chem. 277 (38) :35422-35433 (2002)

• Other Product Names:

  Serine/threonine-protein kinase MAK, Male germ cell-associated kinase, MAK

• Tested Applications:

  WB

• Protein ID:

  13432166

• Physical Properties:

  Liquid