Products for Research Use Only

MAK Antibody

CAT: 0223-60-862Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-862Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.
NCBI Gene ID
4117
Swiss Prot
P20794
Accession Number
P20794
Host
Rabbit
Reactivity
Human
Immunogen
This MAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 595-623 amino acids from the C-terminal region of human MAK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
71 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MAK
NCBI Official Name
Serine/threonine-protein kinase MAK
NCBI Organism
Homo sapiens
Background Reference 01
Fu, Z., et al. Mol. Cell. Biol. 26 (22) :8639-8654 (2006)
Background Reference 02
Ma, A.H., et al. Cancer Res. 66 (17) :8439-8447 (2006)
Background Reference 03
Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)
Background Reference 04
Xia, L., et al. J. Biol. Chem. 277 (38) :35422-35433 (2002)
Other Product Names
Serine/threonine-protein kinase MAK, Male germ cell-associated kinase, MAK
Tested Applications
WB
Protein ID
13432166
Physical Properties
Liquid