UCHL5 Antibody

• Background:

  Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome.

• NCBI Gene ID:

  51377

• Swiss Prot:

  Q9Y5K5

• Accession Number:

  Q9Y5K5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This UCHL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the Central region of human UCHL5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  UCHL5

• NCBI Official Name:

  Ubiquitin carboxyl-terminal hydrolase isozyme L5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nishio, K., et al. Biochem. Biophys. Res. Commun. 390 (3) :855-860 (2009)

• Background Reference 02:

  Yao, T., et al. Mol. Cell 31 (6) :909-917 (2008)

• Background Reference 03:

  Koulich, E., et al. Mol. Biol. Cell 19 (3) :1072-1082 (2008)

• Background Reference 04:

  Qiu, X.B., et al. EMBO J. 25 (24) :5742-5753 (2006)

• Other Product Names:

  Ubiquitin carboxyl-terminal hydrolase isozyme L5, UCH-L5, Ubiquitin C-terminal hydrolase UCH37, Ubiquitin thioesterase L5, UCHL5, UCH37

• Tested Applications:

  WB

• Protein ID:

  108936023

• Physical Properties:

  Liquid