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SF3A2 Antibody

CAT: 0223-60-831Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-831Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.
NCBI Gene ID
8175
Swiss Prot
Q15428
Accession Number
Q15428
Host
Rabbit
Reactivity
Human
Immunogen
This SF3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human SF3A2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SF3A2
NCBI Official Name
Splicing factor 3A subunit 2
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 02
Tanackovic, G., et al. Mol. Biol. Cell 16 (3) :1366-1377 (2005)
Background Reference 03
Nesic, D., et al. J. Cell. Sci. 117 (PT 19), 4423-4433 (2004) :
Background Reference 04
Takenaka, K., et al. Biochem. J. 382 (PT 1), 223-230 (2004) :
Other Product Names
Splicing factor 3A subunit 2, SF3a66, Spliceosome-associated protein 62, SAP 62, SF3A2, SAP62
Tested Applications
WB
Protein ID
20141793
Physical Properties
Liquid

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