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TTPA Antibody

CAT: 0223-60-826Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-826Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.
NCBI Gene ID
7274
Swiss Prot
P49638
Accession Number
P49638
Host
Rabbit
Reactivity
Human
Immunogen
This TTPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-108 amino acids from the Central region of human TTPA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TTPA
NCBI Official Name
Alpha-tocopherol transfer protein
NCBI Organism
Homo sapiens
Background Reference 01
Zhang, W.X., et al. Lipids 44 (7) :631-641 (2009)
Background Reference 02
Wright, M.E., et al. Cancer Res. 69 (4) :1429-1438 (2009)
Background Reference 03
Fusco, C., et al. J. Child Neurol. 23 (11) :1328-1330 (2008)
Background Reference 04
Rotzoll, D.E., et al. Eur. J. Obstet. Gynecol. Reprod. Biol. 140 (2) :183-191 (2008)
Other Product Names
Alpha-tocopherol transfer protein, Alpha-TTP, TTPA, TPP1
Tested Applications
WB
Protein ID
1351322
Physical Properties
Liquid

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