SYNJ2 Antibody

• Background:

  The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  8871

• Swiss Prot:

  O15056

• Accession Number:

  O15056

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SYNJ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-707 amino acids from the Central region of human SYNJ2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  166 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SYNJ2

• NCBI Official Name:

  Synaptojanin-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)

• Background Reference 02:

  Ieguchi, K., et al. J. Biol. Chem. 282 (32) :23296-23305 (2007)

• Background Reference 03:

  Rossi, M.R., et al. Cancer Genet. Cytogenet. 161 (2) :97-103 (2005)

• Background Reference 04:

  Chuang, Y.Y., et al. Cancer Res. 64 (22) :8271-8275 (2004)

• Other Product Names:

  Synaptojanin-2, Synaptic inositol 1,5-trisphosphate 5-phosphatase 2, SYNJ2, KIAA0348

• Tested Applications:

  WB

• Physical Properties:

  Liquid