SYNJ2 Antibody

• Background :

  The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  8871

• Swiss Prot :

  O15056

• Accession Number :

  O15056

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This SYNJ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-707 amino acids from the Central region of human SYNJ2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  166 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  SYNJ2

• NCBI Official Name :

  Synaptojanin-2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)

• Background Reference 02 :

  Ieguchi, K., et al. J. Biol. Chem. 282 (32) :23296-23305 (2007)

• Background Reference 03 :

  Rossi, M.R., et al. Cancer Genet. Cytogenet. 161 (2) :97-103 (2005)

• Background Reference 04 :

  Chuang, Y.Y., et al. Cancer Res. 64 (22) :8271-8275 (2004)

• Other Product Names :

  Synaptojanin-2, Synaptic inositol 1,5-trisphosphate 5-phosphatase 2, SYNJ2, KIAA0348

• Tested Applications :

  WB

• Physical Properties :

  Liquid