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CASQ2 Antibody

CAT: 0223-60-785Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-785Size:400 µL
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Background
The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq].
NCBI Gene ID
845
Swiss Prot
O14958
Accession Number
O14958
Host
Rabbit
Reactivity
Human
Immunogen
This CASQ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CASQ2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rb
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CASQ2
NCBI Official Name
Calsequestrin-2
NCBI Organism
Homo sapiens
Background Reference 01
Kirchhefer, U., et al. J. Mol. Cell. Cardiol. 49 (1) :95-105 (2010)
Background Reference 02
Wong, C.H., et al. Forensic Sci. Int. 192 (1-3), 53-55 (2009) :
Background Reference 03
Liu, J., et al. Am. J. Physiol., Cell Physiol. 297 (1), C152-C159 (2009) :
Background Reference 04
Hayashi, M., et al. Circulation 119 (18) :2426-2434 (2009)
Other Product Names
Calsequestrin-2, Calsequestrin, cardiac muscle isoform, CASQ2
Tested Applications
WB
Physical Properties
Liquid

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