PDCD6 Antibody

CAT: 0223-60-784Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-784Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.
NCBI Gene ID
10016
Swiss Prot
O75340
Accession Number
O75340
Host
Rabbit
Reactivity
Human
Immunogen
This PDCD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human PDCD6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PDCD6
NCBI Official Name
Programmed cell death protein 6
NCBI Organism
Homo sapiens
Background Reference 01
Vergarajauregui, S., et al. J. Biol. Chem. 284 (52) :36357-36366 (2009)
Background Reference 02
Okumura, M., et al. Biochem. Biophys. Res. Commun. 386 (1) :237-241 (2009)
Background Reference 03
Suzuki, H., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 64 (PT 11), 974-977 (2008) :
Background Reference 04
Yamada, Y., et al. Cancer Sci. 99 (11) :2193-2199 (2008)
Other Product Names
Programmed cell death protein 6, Apoptosis-linked gene 2 protein, Probable calcium-binding protein ALG-2, PDCD6, ALG2
Tested Applications
WB
Physical Properties
Liquid

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