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KIRREL Antibody

CAT: 0223-60-752Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-752Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762) . The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]) .
NCBI Gene ID
55243
Swiss Prot
Q96J84
Accession Number
Q96J84
Host
Rabbit
Reactivity
Human
Immunogen
This KIRREL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-534 amino acids from the C-terminal region of human KIRREL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KIRREL
NCBI Official Name
Kin of IRRE-like protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Machuca, E., et al. J. Am. Soc. Nephrol. 21 (7) :1209-1217 (2010)
Background Reference 02
Wagner, M.C., et al. J. Biol. Chem. 283 (51) :35579-35589 (2008)
Background Reference 03
Hartleben, B., et al. J. Biol. Chem. 283 (34) :23033-23038 (2008)
Background Reference 04
Harita, Y., et al. J. Biol. Chem. 283 (14) :9177-9186 (2008)
Other Product Names
Kin of IRRE-like protein 1, Kin of irregular chiasm-like protein 1, Nephrin-like protein 1, KIRREL, KIRREL1, NEPH1
Tested Applications
WB
Protein ID
54036152
Physical Properties
Liquid

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