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GGT1 Antibody

CAT: 0223-60-730Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-730Size:400 µL
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Background
The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.
NCBI Gene ID
2678
Swiss Prot
P19440
Accession Number
P19440
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human GGT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GGT1
NCBI Official Name
Gamma-glutamyltranspeptidase 1
NCBI Organism
Homo sapiens
Background Reference 01
Speliotes, E.K., et al. Hepatology 52 (3) :904-912 (2010)
Background Reference 02
Ikeda, M., et al. Scand. J. Clin. Lab. Invest. 70 (3) :171-179 (2010)
Background Reference 03
Fujita, M., et al. Exp. Biol. Med. (Maywood) 235 (3) :335-341 (2010)
Background Reference 04
Kamatani, Y., et al. Nat. Genet. 42 (3) :210-215 (2010)
Other Product Names
Gamma-glutamyltranspeptidase 1, GGT 1, Gamma-glutamyltransferase 1, Glutathione hydrolase 1, Leukotriene-C4 hydrolase, CD224, Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, GGT1, GGT
Tested Applications
WB
Protein ID
93140064
Physical Properties
Liquid

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