GGT1 Antibody

• Background:

  The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.

• NCBI Gene ID:

  2678

• Swiss Prot:

  P19440

• Accession Number:

  P19440

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This GGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human GGT1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Pig, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GGT1

• NCBI Official Name:

  Gamma-glutamyltranspeptidase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Speliotes, E.K., et al. Hepatology 52 (3) :904-912 (2010)

• Background Reference 02:

  Ikeda, M., et al. Scand. J. Clin. Lab. Invest. 70 (3) :171-179 (2010)

• Background Reference 03:

  Fujita, M., et al. Exp. Biol. Med. (Maywood) 235 (3) :335-341 (2010)

• Background Reference 04:

  Kamatani, Y., et al. Nat. Genet. 42 (3) :210-215 (2010)

• Other Product Names:

  Gamma-glutamyltranspeptidase 1, GGT 1, Gamma-glutamyltransferase 1, Glutathione hydrolase 1, Leukotriene-C4 hydrolase, CD224, Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, GGT1, GGT

• Tested Applications:

  WB

• Protein ID:

  93140064

• Physical Properties:

  Liquid