SMAD5 Antibody

• Background:

  Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD) .

• NCBI Gene ID:

  4090

• Swiss Prot:

  Q99717

• Accession Number:

  Q99717

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SMAD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the Central region of human SMAD5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  52 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SMAD5

• NCBI Official Name:

  Mothers against decapentaplegic homolog 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yang, J., et al. Circ. Res. 107 (2) :252-262 (2010)

• Background Reference 02:

  Tao, S., et al. Dev. Growth Differ. 52 (4) :335-342 (2010)

• Background Reference 03:

  Middlebrook, B.S., et al. Endocrinology 150 (12) :5208-5217 (2009)

• Background Reference 04:

  Su, D., et al. J. Biol. Chem. 284 (18) :12153-12164 (2009)

• Other Product Names:

  Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, JV5-1, SMAD family member 5, SMAD 5, Smad5, hSmad5, SMAD5, MADH5

• Tested Applications:

  WB

• Protein ID:

  13959566

• Physical Properties:

  Liquid