C8B Antibody

• Background :

  C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.

• NCBI Gene ID :

  732

• Swiss Prot :

  P07358

• Accession Number :

  P07358

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This C8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-422 amino acids from the C-terminal region of human C8B.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  67 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  C8B

• NCBI Official Name :

  Complement component C8 beta chain

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

• Background Reference 02 :

  Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

• Background Reference 03 :

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 04 :

  Gancz, D., et al. Mol. Immunol. 47 (2-3), 310-317 (2009) :

• Other Product Names :

  Complement component C8 beta chain, Complement component 8 subunit beta, C8B

• Tested Applications :

  WB

• Protein ID :

  20141201

• Physical Properties :

  Liquid