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C8B Antibody

CAT: 0223-60-701Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-701Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.
NCBI Gene ID
732
Swiss Prot
P07358
Accession Number
P07358
Host
Rabbit
Reactivity
Human
Immunogen
This C8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-422 amino acids from the C-terminal region of human C8B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
67 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
C8B
NCBI Official Name
Complement component C8 beta chain
NCBI Organism
Homo sapiens
Background Reference 01
Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)
Background Reference 02
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)
Background Reference 03
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 04
Gancz, D., et al. Mol. Immunol. 47 (2-3), 310-317 (2009) :
Other Product Names
Complement component C8 beta chain, Complement component 8 subunit beta, C8B
Tested Applications
WB
Protein ID
20141201
Physical Properties
Liquid

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