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UBE2R2 Antibody

CAT: 0223-60-700Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-700Size:400 µL
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Background
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.
NCBI Gene ID
54926
Swiss Prot
Q712K3
Accession Number
Q712K3
Host
Rabbit
Reactivity
Human
Immunogen
This UBE2R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the Central region of human UBE2R2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
27 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
UBE2R2
NCBI Official Name
Ubiquitin-conjugating enzyme E2 R2
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)
Background Reference 03
Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)
Background Reference 04
Ferreira, M.A., et al. Nat. Genet. 40 (9) :1056-1058 (2008)
Other Product Names
Ubiquitin-conjugating enzyme E2 R2, Ubiquitin carrier protein R2, Ubiquitin-conjugating enzyme E2-CDC34B, Ubiquitin-protein ligase R2, UBE2R2, CDC34B, UBC3B
Tested Applications
WB
Protein ID
74749761
Physical Properties
Liquid

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