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UBE2D2 Antibody

CAT: 0223-29-820Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-820Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na (+) and pH independent, while the transport of neutral amino acids is Na (+) and pH dependent (Hatanaka et al., 2001) .
NCBI Gene ID
7322
Swiss Prot
P62837
Accession Number
NP_003330
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2D2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Apoptosis, Homeostasis
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UBE2D2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
60 kDa, 61 kDa
Applications Notes
UBE2D2 antibody can be used for detection of UBE2D2 by ELISA at 1:1562500. UBE2D2 antibody can be used for detection of UBE2D2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
UBE2D2
NCBI Official Name
Ubiquitin-conjugating enzyme E2D 2
NCBI Organism
Homo sapiens
Background Reference 01
Desforges, M., Am. J. Physiol., Cell Physiol. 290 (1), C305-C312 (2006) .
Other Product Names
UBE2D2, E2 (17) KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Tested Applications
ELISA, WB, IHC
Protein ID
4507775
Physical Properties
Liquid

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