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NXT1 Antibody

CAT: 0223-60-697Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-697Size:400 µL
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Background
The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein) - and CRM1 (required for chromosome region maintenance) -dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
NCBI Gene ID
29107
Swiss Prot
Q9UKK6
Accession Number
Q9UKK6
Host
Rabbit
Reactivity
Mouse
Immunogen
This NXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-111 amino acids from the C-terminal region of human NXT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
16 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NXT1
NCBI Official Name
NTF2-related export protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)
Background Reference 02
Forler, D., et al. Nat. Biotechnol. 21 (1) :89-92 (2003)
Background Reference 03
Katahira, J., et al. J. Biol. Chem. 277 (11) :9242-9246 (2002)
Background Reference 04
Wiegand, H.L., et al. Mol. Cell. Biol. 22 (1) :245-256 (2002)
Other Product Names
NTF2-related export protein 1, Protein p15, NXT1
Tested Applications
WB
Protein ID
18203504
Physical Properties
Liquid

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