MEFV Antibody

• Background :

  This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome.

• NCBI Gene ID :

  4210

• Swiss Prot :

  O15553

• Accession Number :

  O15553

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This MEFV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-445 amino acids from the Central region of human MEFV.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  86 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  MEFV

• NCBI Official Name :

  Pyrin

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Cosan, F., et al. Arthritis Rheum. 62 (11) :3232-3236 (2010)

• Background Reference 02 :

  Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

• Background Reference 03 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 04 :

  He, X., et al. Pediatr. Nephrol. 25 (10) :2077-2082 (2010)

• Other Product Names :

  Pyrin, Marenostrin, MEFV, MEF

• Tested Applications :

  WB

• Physical Properties :

  Liquid