MEFV Antibody

• Background:

  This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome.

• NCBI Gene ID:

  4210

• Swiss Prot:

  O15553

• Accession Number:

  O15553

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MEFV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-445 amino acids from the Central region of human MEFV.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  86 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MEFV

• NCBI Official Name:

  Pyrin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cosan, F., et al. Arthritis Rheum. 62 (11) :3232-3236 (2010)

• Background Reference 02:

  Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

• Background Reference 03:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 04:

  He, X., et al. Pediatr. Nephrol. 25 (10) :2077-2082 (2010)

• Other Product Names:

  Pyrin, Marenostrin, MEFV, MEF

• Tested Applications:

  WB

• Physical Properties:

  Liquid