TIPIN Antibody

• Background :

  Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.

• NCBI Gene ID :

  54962

• Swiss Prot :

  Q9BVW5

• Accession Number :

  Q9BVW5

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  35 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  TIPIN

• NCBI Official Name :

  TIMELESS-interacting protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Kemp, M.G., et al. J. Biol. Chem. 285 (22) :16562-16571 (2010)

• Background Reference 02 :

  Leman, A.R., et al. J. Cell. Sci. 123 (PT 5), 660-670 (2010) :

• Background Reference 03 :

  Utge, S.J., et al. PLoS ONE (2), E9259 (2010) :

• Background Reference 04 :

  Unsal-Kacmaz, K., et al. Mol. Cell. Biol. 27 (8) :3131-3142 (2007)

• Other Product Names :

  TIMELESS-interacting protein, TIPIN

• Tested Applications :

  WB

• Protein ID :

  296452932

• Physical Properties :

  Liquid