DNER Antibody

• Background:

  Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity) .

• NCBI Gene ID:

  92737

• Swiss Prot:

  Q8NFT8

• Accession Number:

  Q8NFT8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DNER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 708-736 amino acids from the C-terminal region of human DNER.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  78 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  DNER

• NCBI Official Name:

  Delta and Notch-like epidermal growth factor-related receptor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kurisu, J., et al. J. Neurochem. 113 (6) :1598-1610 (2010)

• Background Reference 02:

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 03:

  Park, J.R., et al. Cell Prolif. 43 (1) :19-28 (2010)

• Background Reference 04:

  Ramachandran, P., et al. J. Proteome Res. 5 (6) :1493-1503 (2006)

• Other Product Names:

  Delta and Notch-like epidermal growth factor-related receptor, DNER, BET

• Tested Applications:

  WB

• Protein ID:

  74730301

• Physical Properties:

  Liquid