RECQL4 Antibody

• Background:

  The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes. [provided by RefSeq].

• NCBI Gene ID:

  9401

• Swiss Prot:

  O94761

• Accession Number:

  O94761

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This RECQL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1162 amino acids from the C-terminal region of human RECQL4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  133 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RECQL4

• NCBI Official Name:

  ATP-dependent DNA helicase Q4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rossi, M.L., et al. DNA Repair (Amst.) 9 (7) :796-804 (2010)

• Background Reference 02:

  Singh, D.K., et al. Aging Cell 9 (3) :358-371 (2010)

• Background Reference 03:

  Thangavel, S., et al. Mol. Cell. Biol. 30 (6) :1382-1396 (2010)

• Background Reference 04:

  Xu, X., et al. EMBO J. 28 (19) :3005-3014 (2009)

• Other Product Names:

  ATP-dependent DNA helicase Q4, DNA helicase, RecQ-like type 4, RecQ4, RTS, RecQ protein-like 4, RECQL4, RECQ4

• Tested Applications:

  WB

• Physical Properties:

  Liquid