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RFFL Antibody

CAT: 0223-60-548Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-548Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RFFL has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.
NCBI Gene ID
117584
Swiss Prot
Q8WZ73
Accession Number
Q8WZ73
Host
Rabbit
Reactivity
Human
Immunogen
This RFFL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the C-terminal region of human RFFL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RFFL
NCBI Official Name
E3 ubiquitin-protein ligase rififylin
NCBI Organism
Homo sapiens
Background Reference 01
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 02
Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)
Background Reference 03
Newton-Cheh, C., et al. Nat. Genet. 41 (4) :399-406 (2009)
Background Reference 04
Liao, W., et al. Curr. Biol. 18 (9) :641-649 (2008)
Other Product Names
HGNC:24821
Tested Applications
WB
Protein ID
74760639
Physical Properties
Liquid

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