DHODH Antibody

CAT: 0223-60-535Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-535Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.
NCBI Gene ID
1723
Swiss Prot
Q02127
Accession Number
Q02127
Host
Rabbit
Reactivity
Human
Immunogen
This DHODH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human DHODH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DHODH
NCBI Official Name
Dihydroorotate dehydrogenase (quinone), mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Hail, N. Jr., et al. Free Radic. Biol. Med. 49 (1) :109-116 (2010)
Background Reference 02
Ng, S.B., et al. Nat. Genet. 42 (1) :30-35 (2010)
Background Reference 03
Grabar, P.B., et al. Ann. Rheum. Dis. 68 (8) :1367-1368 (2009)
Background Reference 04
Pawlik, A., et al. Pharmacogenomics 10 (2) :303-309 (2009)
Other Product Names
Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase, DHODH
Tested Applications
WB
Protein ID
56405372
Physical Properties
Liquid

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