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MRPL24 Antibody

CAT: 0223-60-527Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-527Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL24 is a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24) .
NCBI Gene ID
79590
Swiss Prot
Q96A35
Accession Number
Q96A35
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MRPL24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-214 amino acids from the C-terminal region of human MRPL24.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MRPL24
NCBI Official Name
39S ribosomal protein L24, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Zhang, Z., et al., Genomics 81 (5) :468-480 (2003) .
Background Reference 02
O'Brien, T.W., et al., J. Biol. Chem. 275 (24) :18153-18159 (2000) .
Background Reference 03
Kenmochi, N., et al., Genomics 77 (1-2), 65-70 (2001) .
Other Product Names
39S ribosomal protein L24, mitochondrial, L24mt, MRP-L24, MRPL24
Tested Applications
WB
Protein ID
74751733
Physical Properties
Liquid

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