MRPL28 Antibody

CAT: 0223-60-346Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-346Size:400 µL
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion.
NCBI Gene ID
10573
Swiss Prot
Q13084
Accession Number
Q13084
Host
Rabbit
Reactivity
Human
Immunogen
This MRPL28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human MRPL28.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Symbol
MRPL28
NCBI Official Name
39S ribosomal protein L28, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 02
Martin, J., et al. Nature 432 (7020) :988-994 (2004)
Background Reference 03
Zhang, Z., et al. Genomics 81 (5) :468-480 (2003)
Background Reference 04
Koc, E.C., et al. J. Biol. Chem. 276 (47) :43958-43969 (2001)
Other Product Names
39S ribosomal protein L28, mitochondrial, L28mt, MRP-L28, Melanoma antigen p15, Melanoma-associated antigen recognized by T-lymphocytes, MRPL28, MAAT1
Tested Applications
WB, IF
Protein ID
85695426
Physical Properties
Liquid

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