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ACO2 Antibody

CAT: 0223-60-502Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-502Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.
NCBI Gene ID
50
Swiss Prot
Q99798
Accession Number
Q99798
Host
Rabbit
Reactivity
Human, Rat
Immunogen
This ACO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 amino acids from the Central region of human ACO2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
85 kDa
Fragment
Rabbit Ig
Symbol
ACO2
NCBI Official Name
Aconitate hydratase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Juang, H.H., Mol. Genet. Metab. 81 (3) :244-252 (2004) .
Background Reference 02
Bota, D.A., et al., Nat. Cell Biol. 4 (9) :674-680 (2002) .
Background Reference 03
Gruer, M.J., et al., Trends Biochem. Sci. 22 (1) :3-6 (1997) .
Background Reference 04
Klausner, R.D., et al., Mol. Biol. Cell 4 (1) :1-5 (1993) .
Other Product Names
Aconitate hydratase, mitochondrial, Aconitase, Citrate hydro-lyase, ACO2
Tested Applications
WB, IHC-P
Protein ID
6686275
Physical Properties
Liquid

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