HMOX2 Antibody

• Background:

  Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.

• NCBI Gene ID:

  3163

• Swiss Prot:

  P30519

• Accession Number:

  P30519

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HMOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human HMOX2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  HMOX2

• NCBI Official Name:

  Heme oxygenase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Abdel Aziz, M.T., et al. Andrologia 42 (4) :236-241 (2010)

• Background Reference 02:

  Wang, Y., et al. J. Hum. Genet. 55 (8) :490-494 (2010)

• Background Reference 03:

  He, J.Z., et al. J. Biol. Chem. 285 (13) :9452-9461 (2010)

• Background Reference 04:

  Zhong, J.L., et al. Free Radic. Biol. Med. 48 (2) :196-206 (2010)

• Other Product Names:

  Heme oxygenase 2, HO-2, HMOX2, HO2

• Tested Applications:

  WB

• Protein ID:

  1170328

• Physical Properties:

  Liquid